In Vitro Cytotoxicity and Antioxidant Studies of Dovyallis caffra-Mediated Cassiterite (SnO2) Nanoparticles

Many medicinal plants found in Africa, such as Dovyallis caffra, have been reported to contain various bioactive compounds, which reduce metal salts into their corresponding metal-based nanoparticles. In this paper, the evaluation of synthesis, characterization, and biological properties caffra-mediated cassiterite (SnO2) nanoparticles was carried out. The physicochemical synthesized material were investigated using X-ray diffraction (XRD), energy dispersive analysis (EDX), scanning electron microscopy (SEM), transmission (TEM) techniques. characterization studies revealed that possessed a single tetragonal SnO2 phase, having cluster-like foam appearance an irregular spherical morphology with diameters ranging from 6.57 34.03 nm. screening prepared exhibited cytotoxicity against MCF-7 breast cancer cells, IC50 value 62.33 µg mL−1, better than standard drug 5-fluorouracil, 71.21 mL−1. radical scavenging potential nanoparticles, DPPH assay, showed it slightly activity ascorbic acid, common antioxidant. These results suggest possess simultaneously generate scavenge excess ROS, turn exhibition good antioxidant properties.